Orchid Chemicals & Pharmaceuticals Ltd. is a leading pharmaceutical company headquartered in Chennai, India involved in the development, manufacture and marketing of diverse bulk actives, formulations and nutraceuticals. With exports spanning more than 75 countries, Orchid is the largest manufacturer-exporter of cephalosporin bulk actives in India and is ranked amongst the Top 5-cephalosporin producers in the world.
In India, the Pharmaceutical business of Orchid Chemicals & Pharmaceuticals Ltd. is focused on Pyrimidine Compounds, Heterocyclic Compounds as Phosphodiesterase Inhibitors, Histone Deacetylase Inhibitors, Dipeptidyl Peptidase IV Inhibitors, Histone Deacetylase Inhibitors.
Orchid Chemicals & Pharmaceuticals Ltd. filed patent application numbered 3097/CHE/2007 that is titled A METHOD FOR THE PREPARATION OF DULOXETINE HYDROCHLORIDE. This patent application has been granted as Patent Number 280121.
The invention covers the field of chemical compounds. The invention related to an improved process for the preparation of Duloxetine and its intermediate propanamine by reacting hydroxylamine with fluoronaphthalene in the presence of a base, wherein the improves lies in conducting the reaction in the absence of solvent.
During patent examination, the patent examiner raised objections under Section 3(d) of the Indian Patents Act, wherein the examiner stated that the claims 1-3, 5 and 6 are statutorily non-patentable as they are not an invention and process is a known process.
As a response, it has been claimed that Present application process has technical advantage and economical significance and it is found to be inventive as it is: Eco- friendly, residual solvent content avoided, reduced cost of production, easier handling in commercial sale and compound isolated with good yield and purity.
Advocate Rahul Dev is a Patent Attorney & International Business Lawyer practicing Technology, Intellectual Property & Corporate Laws. He is reachable at rd (at) patentbusinesslawyer (dot) com & @rdpatentlawyer on Twitter.
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