Council of Scientific and Industrial Research and Department of Biotechnology Receives a Patent for Amino-acid Conjugates of Curcumin

The CSIR mandate in the Biology and Biotechnology Sector is to develop commercially viable products/technologies by carrying out research in genomics and molecular medicine, r-DNA technology, protein engineering, drug/nutraceutical development, DNA and immuno diagnostics, synthetic chemistry, toxicology, fermentation technology, analytical biochemistry, environmental sciences, besides bioprospecting, developing novel agro-technologies, and conserving biodiversity.

Whereas in December 2015, the Department of Biotechnology launched the National Biotechnology Development Strategy 2015–2020 programme. The stated aim of the programme is to intensify research in the fields of vaccines, humane genome, infectious and chronic diseases, crop science, animal agriculture and aqua culture, food and nutrition, environmental management and technologies for clean energy. The mission, through stakeholders in the biotechnology and technology domains is backed with significant investments to create new products, creating a strong infrastructure for research and development, commercialization, and empowering human resources scientifically and technologically.

Council of Scientific and Industrial Research and Department of Biotechnology filed patent application numbered 405/DEL/2009 that is titled as “A PROCESS FOR THE PREPARATION OF WATER-SOLUBLE AMINO ACID CONJUGATES OF CURCUMIN.” This patent application has been granted as Patent Number 290961.

The invention covers chemical compounds. The invention relates to Amino-acid conjugates of curcumin are prepared by the process of present invention by synthetic methodology that envisaged facile reaction of the N-protected (t-BOC) amino acids with curcumin and included an improved accelerated protocol for the de-protection of f-BOC group to afford the formation of amino-acid conjugates of curcumin. The yield of amino-acid conjugates of curcumin as obtained by present method is significantly high.

During patent examination, the patent examiner raised objections under Section 3(d) of the Indian Patents Act, wherein the examiner stated that claim(s) 1-10 are statutorily non-patentable.

As a response, the differentiation was made on the basis of process and scientific features.

Advocate Rahul Dev is a Patent Attorney & International Business Lawyer practicing Technology, Intellectual Property & Corporate Laws. He is reachable at rd (at) patentbusinesslawyer (dot) com & @rdpatentlawyer on Twitter.

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