patent number 375367 has been granted to BAYER PHARMA AKTIENGESELLSCHAFT that is titled ANTIBODY DRUG CONJUGATES (ADCS) WITH KINESIN SPINDLE PROTEIN (KSP). The patent applicant responded to this objection by stating that the cited compounds are pyrazole derivatives or pyrrole derivatives. The claimed invention indicates the cytotoxic effects of claimed drug conjugates demonstrating the cytotoxicity in various cell lines, including human lung carcinoma cells, human pancreas carcinoma cells, and human breast carcinoma cells. This patent falls under the category of Chemical. Overall, this patent covers a conjugate of a binder or derivative thereof with one or more active compound molecules, the active compound molecule being a kinesin spindle protein inhibitor attached to the binder via a linker L.